whenever i’m having a bad day i remind myself that at least spiders can’t fly
Anonymous asked "Please write more JasCas I need more YOURE A RAD WRITER *~*"
AHHH THANK YOU! :D :D
You should send me prompts! Because I’m awful at thinking of them myself x_x
- Damian Wayne: cOMIN OUTTA MY GRAVE AND I BEEN DOIN JUST FINE
Anonymous asked "How much people in your family who have had cancer would be a good prompt to test for Lynch syndrome, if you know?"
What a crazy question, because the current lab I’m rotating in actually studies Lynch syndrome aka hereditary nonpolyposis colorectal cancer (HNPCC). So when I saw this I had to do a double take.
There’s actually a criteria that’s been established for use in research and in clinics when characterizing someone as having Lynch syndrome. It’s known as the Amsterdam Criteria (after the location of the convention it was decided at). I think you have to hit all 4:
- 3 or more family members, one of whom is a first degree relative (parent, child, or sibling) of the other 2, with a confirmed diagnosis of HNPCC
- 2 successive affected generations (for example, grandma has it, as well as her son, your father)
- 1 or more of the HNPCC-related cancers diagnosed before the age of 50
- Exclusion of another type of colorectal cancer, familial adenomatous polyposis (basically this cancer progresses using different pathways than HNPCC)
Keep in mind this only deals with HNPCC. If someone else in your family has colorectal cancer that’s not HNPCC, it may not be considered Lynch syndrome. HNPCC can be diagnosed by specific genetic markers.
As always, the word you should trust is a doctor or genetic counselor, but I hope this helped!